ncRNA name | FAK siRNA |
ncRNA Category | siRNA |
Disease name | proliferative vitreoretinopathy (PVR) |
Species | Homo sapiens |
Tissues/Cell_line | human RPE cell line ARPE-19 |
Methods | siRNA transfection, flow cytometry, Western blot, adhesion assay |
Expression pattern | associated |
Functional description | FAK siRNA transient transfection significantly reduced FAK protein expression by 71% (P=0.02) and concordantly decreased gel contraction (P=0.0001). |
PubMed ID | 17915217 |
Year | 2007 |
Title | Collagen gel contraction by ARPE-19 cells is mediated by a FAK-Src dependent pathway. |
Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.